The distinguishing sequence characteristics of mouse imprinted genes

  title={The distinguishing sequence characteristics of mouse imprinted genes},
  author={Xiayi Ke and Simon Thomas and David O. Robinson and Andrew Collins},
  journal={Mammalian Genome},
Sequence comparison analysis has been carried out for 31 imprinted mouse genes and a set of 150 control genes. The imprinted genes were found to be associated with significantly reduced numbers of short interspersed transposable elements (SINEs), in particular SINE Alu repeats. This is similar to recent analyses of human imprinted genes and supports the suggestion that there is either active selection against SINE elements in imprinted regions or a reduced rate of insertion of these elements… CONTINUE READING
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A genome-wide screen for normally methylated human CpG islands that can identify novel imprinted genes

  • PO Onyango, E Perlman, F Flam
  • Genome Res
  • 2002

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