The dissolution and solid-state behaviours of coground ibuprofen–glucosamine HCl

@article{AlHamidi2015TheDA,
  title={The dissolution and solid-state behaviours of coground ibuprofen–glucosamine HCl},
  author={Hiba Al-Hamidi and K. Asare-Addo and S. Desai and Mike Kitson and A. Nokhodchi},
  journal={Drug Development and Industrial Pharmacy},
  year={2015},
  volume={41},
  pages={1682 - 1692}
}
Abstract The cogrinding technique is one of most effective methods for improving the dissolution of poorly water-soluble drugs and it is superior to other approaches from an economical as well as an environmental standpoint, as the technique does not require any toxic organic solvents. Present work explores the role of d-glucosamine HCl (GL) as a potential excipient to improve dissolution of a low melting point drug, ibuprofen (Ibu), using physical mixtures and coground formulations. The… Expand
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  • K. Asare-Addo, Maen Alshafiee, +9 authors B. Conway
  • Materials Science, Medicine
  • European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
  • 2019
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