The dissemination of multiple sclerosis: A Viking saga? A historical essay

@article{Poser1994TheDO,
  title={The dissemination of multiple sclerosis: A Viking saga? A historical essay},
  author={Charles M. Poser},
  journal={Annals of Neurology},
  year={1994},
  volume={36}
}
  • C. Poser
  • Published 1 December 1994
  • History
  • Annals of Neurology
The highest prevalence rates for multiple sclerosis are found in Iceland, Scandinavia, the British Isles, and the countries settled by their inhabitants and their descendants, that is, the United States, Canada, Australia, and New Zealand. This suggests that the Vikings may have been instrumental in disseminating the genetic susceptibility to the disease in those areas as well as in other parts of the world. The Vikings raided in most European countries and settled in Normandy and in Sicily and… 
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References

SHOWING 1-10 OF 27 REFERENCES
Multiple sclerosis in Iceland, with observations on the alleged epidemic in the Faroe Islands
TLDR
The profile of multiple sclerosis in Iceland based on a total population study from 1900 to 1990 is reviewed and no evidence was found to support the hypothesis that an epidemic of MS had occurred in Iceland following the arrival of British, Canadian, and American troops during the Second World War.
Multiple sclerosis is prevalent in the zoroastrians (Parsis) of India
TLDR
The prevalence rate of clinically definite multiple sclerosis in the distinct but tiny Zoroastrian (largely Parsi) community in the adjacent cities of Bombay and Poona is determined, finding rates much higher than the low rates believed to be prevalent in India, and comparable with those found in parts of Europe and the United States.
MULTIPLE SCLEROSIS: FROM THE STANDPCINT OF GEOGRAPHIC DISTRIBUTION AND RACE
TLDR
The results of the tabulation of multiple sclerosis as one of the defects found in drafted men are plotted and it shows that the maximum rate was found in Michigan and Minnesota, in which there were eighteen persons with this disease per 100,000.
Epidemiology of multiple sclerosis in Northwestern Sardinia: further evidence for higher frequency in Sardinians compared to other Italians.
TLDR
The present study confirms the higher frequency of MS among Sardinians compared to other Italian populations and suggests a role of environmental and genetic factors in determining the notable difference in MS risk between Sardinia and the rest of Italy.
INCIDENCE OF MULTIPLE SCLEROSIS IN UNITED STATES TROOPS
TLDR
During the recent mobilization the neuropsychiatric officers examined approximately 3,500,000 men, draftees and volunteers, and a total of 69,394 cases of nervous and mental disease and defects were identified.
The distribution of multiple sclerosis in the United Kingdom.
TLDR
The fall in incidence observed in the Orkney Islands, possibly reflecting decline in an exogenous agent interacting with susceptibility factors, is consistent with this multifactorial hypothesis.
The problem of disseminated sclerosis.
TLDR
This subject ought to be reviewed once again in the hope of arousing fresh interest in a problem which, on humanitarian grounds alone, deserved the attention of those qualified to take part in its investigation.
A reappraisal of the epidemiology of multiple sclerosis in Olmsted County, Minnesota
A review of multiple sclerosis (MS) case reports, using the unified record system at the Mayo Clinic for the Olmsted County population, revealed age- and sex-adjusted prevalence rates per 100,000
Does the history of multiple sclerosis go back as far as the 14th century?
  • R. Medaer
  • Medicine
    Acta neurologica Scandinavica
  • 1979
A number of documents written before or shortly after the death of St. Lidwina of Schiedam (1380‐1433) surprised us by their very accurate description of symptoms which for the most part correspond
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