The discovery of moriniafungin, a novel sordarin derivative produced by Morinia pestalozzioides.
@article{Basilio2006TheDO, title={The discovery of moriniafungin, a novel sordarin derivative produced by Morinia pestalozzioides.}, author={A Basilio and Michael C. Justice and Guy H. Harris and Gf Bills and Javier Collado and Mercedes de la Cruz and Mar{\'i}a Teresa D{\'i}ez and Pilar Hernández and Paul A. Liberator and Jennifer Nielsen Kahn and Fernando Peláez and Gonzalo Platas and Dennis M. Schmatz and M Shastry and Jos{\'e} Ruben Tormo and Gregers Rom Andersen and Francisca Vicente}, journal={Bioorganic \& medicinal chemistry}, year={2006}, volume={14 2}, pages={ 560-6 } }
28 Citations
Sordarin Diterpene Glycosides with an Unusual 1,3-Dioxolan-4-one Ring from the Zoanthid-Derived Fungus Curvularia hawaiiensis TA26-15.
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Six new sordarin tetracyclic diterpene glycoside glycosides, moriniafungins B-G, and anew sordaricin tetrACYclicDiterPene, sordARicin B, together with two known analogues were isolated from the zoanthid-derived fungus Curvularia hawaiiensis TA26-15.
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Results suggest moriniafungin has potential as a control agent of postharvest diseases caused by Rhizopus spp.
Distribution of the antifungal agents sordarins across filamentous fungi.
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Amide, cyclohexenone, and cyclohexenone–sordaricin derivatives from the endophytic fungus Xylaria plebeja PSU-G30
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Studies on Morinia: recognition of Morinia longiappendiculata sp. nov. as a new endophytic fungus, and a new circumscription of Morinia pestalozzioides.
- BiologyMycologia
- 2006
Comparative sequence analysis of the ITS rDNA region and fragments of the translation elongation factor 1alpha, actin and chitin synthase 1 genes and the study of the HPLC profiles of the M. pestalozzioides isolates supported the recognition of the new species, Morinia longiappendiculata sp.
Studies on Morinia: Recognition of Morinia longiappendiculata sp. nov. as a new endophytic fungus, and a new circumscription of Morinia pestalozzioides
- 2006
Comparative sequence analysis of the ITS rDNA region and fragments of the translation elongation factor 1α, actin and chitin synthase 1 genes and the study of the HPLC profiles of the M. longiappendiculata and M. pestalozzioides isolates supported the recognition of the new species.
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Results indicated a first production phase of secondary metabolite dominated by peptides, after 21–23 days, which suggests value in exploring extended cultivation times to identify novel bioactive fungal compounds.
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It is found that the addition of XAD-16 resin resulted in four-fold higher titers in the production of cerulenin when compared to the best production conditions described in literature for the original fungal producer strain, Cephalosporium caerulens KF-140 (=Sarocladium oryzae).
FR290581, a novel sordarin derivative: synthesis and antifungal activity.
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