The discovery of heroin

  title={The discovery of heroin},
  author={Walter Sneader},
  journal={The Lancet},
  • W. Sneader
  • Published 21 November 1998
  • Medicine
  • The Lancet
Toxicological studies of opiate-related death
Support for the notion that polydrug use and recent opiate abstinence are important risk factors for opiate overdose death is provided, in a larger sample of deceased drug addicts.
The effects of ethanol on the metabolism of heroin in C57BL/6J mice in vivo and in vitro
Findings indicated that ethanol had small modulating effect on the metabolism of heroin, but no changes in the concentration vs. time curves of 6MAM or morphine in brain were found and results were reflected in locomotor activity.
Pharmacological Management of Heroin Withdrawal Syndrome
The pharmacological management of heroin withdrawal syndrome in the past century has progressed from the introduction of methadone to the utilization of clonidine and buprenorphine, an opioid agonist/antagonist endorsed for the treatment of heroin withdrawals in 2000.
Confirmation of recent heroin abuse: Accepting the challenge.
This paper aims to provide an overview of the wide variety of heroin abuse biomarkers described in the literature and to review them regarding their utility and reliability in daily routine analysis.
Developing a vaccine against multiple psychoactive targets: a case study of heroin.
This review discusses the opiate scaffolding and hapten design considerations to confer immunogenicity as well as the specificity of the immune response towards structurally similar opiates, and detail different strategies employed in the design of immunoconjugates for a vaccine-based therapy for heroin addiction treatment.


Historical Aspects of Pharmacologic Research at Bayer 1890–1990
The company that became Aktiengesellschaft Farbenfabriken vorm. Friedr. Bayer und Co. in 1881 was founded in 1863 by the merchant Friedrich Bayer (1825-1880) and the master dyer Johann Friedrich
The American Dream?
Then listen. My mother died the night that I was born and I never knew my father; I doubt my mother did. But, I wasn’t alone, because lying with the placenta...there was someone
Drug prototypes and their exploitation
Source of drug Prototypes Drug Prototypes from Minerals Prototypes for Plants and Animals and Effects Perceived by Observers Effects Observed During Laboratory Experiments.
Studien über Morphin
Heroin: new facts about an old myth.