The discovery of a novel sodium channel in the cockroach Periplaneta americana: evidence for an early duplication of the para-like gene.


Voltage-gated sodium channels (Na(v) channels) belong to a superfamily of ion channels which play an essential role in membrane excitability. Only one gene encoding Na(v) channels has been characterized so far in insects. Here, we have cloned one full-length cDNA encoding a conventional insect Na(v) channel (PaNa(v)1) and two full-length cDNAs encoding… (More)
DOI: 10.1016/j.ibmb.2009.09.006


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