The discovery approaches and detection methods of microRNAs

@article{Huang2010TheDA,
  title={The discovery approaches and detection methods of microRNAs},
  author={Yong Can Huang and Quan Zou and Sheng Peng Wang and Shun Ming Tang and Guo Zheng Zhang and Xing Jia Shen},
  journal={Molecular Biology Reports},
  year={2010},
  volume={38},
  pages={4125-4135}
}
MicroRNAs (miRNAs) are small, highly conserved, non-coding RNAs that regulate gene expression of target mRNAs through cleavage or translational inhibition. Computer-based approaches for miRNA gene identification are being considered as indispensable in miRNAs research. Similarly, experimental approaches for detection of miRNAs are crucial to the testing and validating of computational algorithms. The detection of miRNAs in tissues or cells can supply valuable information for investigating the… CONTINUE READING
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