The direct effect of estrogen on cell viability and apoptosis in human gastric cancer cells

  title={The direct effect of estrogen on cell viability and apoptosis in human gastric cancer cells},
  author={J. Qin and Min Liu and Q. Ding and X. Ji and Y. Hao and Xiao-min Wu and J. Xiong},
  journal={Molecular and Cellular Biochemistry},
  • J. Qin, Min Liu, +4 authors J. Xiong
  • Published 2014
  • Biology, Medicine
  • Molecular and Cellular Biochemistry
  • Epidemiology researches indicated that gastric cancer is a male-predominant disease; both expression level of estrogen and expression pattern of estrogen receptors (ERs) influence its carcinogenesis. But the direct effect of estrogen on gastric cancer cells is still unclear. This study aimed to explore the direct effect of β-estradiol (E2) on gastric cancer cells. SGC7901 and BGC823 were treated with a serial of concentrations of E2. The survival rates of both the cell lines were significantly… CONTINUE READING
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