The direct and indirect allogeneic presentation pathway during acute rejection after human cardiac transplantation.

Abstract

Alloreactive T cells may be activated via a direct or an indirect antigen presentation pathway. We questioned whether the frequency of interferon (IFN)-gamma producing cells determined by enzyme-linked immunospot (ELISPOT) assay is an effective tool to monitor the direct and/or indirect presentation pathway. Secondly, we wondered whether early and late… (More)

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@article{Besouw2005TheDA, title={The direct and indirect allogeneic presentation pathway during acute rejection after human cardiac transplantation.}, author={Nicole M van Besouw and Joke M. Zuijderwijk and Leonard Maria Bernardus Vaessen and A. H. M. M. Balk and A. P. W. M. Maat and Peter H van der Meide and W R Weimar}, journal={Clinical and experimental immunology}, year={2005}, volume={141 3}, pages={534-40} }