The dimeric form of Ca2+-ATPase is involved in Ca2+ transport in the sarcoplasmic reticulum.

@article{Ushimaru2008TheDF,
  title={The dimeric form of Ca2+-ATPase is involved in Ca2+ transport in the sarcoplasmic reticulum.},
  author={M. Ushimaru and Y. Fukushima},
  journal={The Biochemical journal},
  year={2008},
  volume={414 3},
  pages={
          357-61
        }
}
To identify the functional unit of Ca(2+)-ATPase in the sarcoplasmic reticulum, we assessed Ca(2+)-transport activities occurring on sarcoplasmic reticulum membranes with different combinations of active and inactive Ca(2+)-ATPase molecules. We prepared heterodimers, consisting of a native Ca(2+)-ATPase molecule and a Ca(2+)-ATPase molecule inactivated by FITC labelling, by fusing vesicles loaded with each type of Ca(2+)-ATPase. The heterodimers exhibited neither Ca(2+) transport nor ATP… Expand
7 Citations
ANS Interacts with the Ca2+-ATPase Nucleotide Binding Site
The P-Type ATPase Superfamily
  • 90

References

SHOWING 1-10 OF 33 REFERENCES
Monomeric sarcoplasmic reticulum Ca(2+)-ATPase is functionally active.
  • 2
Rotational dynamics and protein-protein interactions in the Ca-ATPase mechanism.
  • 45
Transient state kinetic effects of calcium ion on sarcoplasmic reticulum adenosine triphosphatase.
  • 95
...
1
2
3
4
...