The dilatatory action of adenosine on pial arteries of cats and its inhibition by theophylline

@article{Wahl1976TheDA,
  title={The dilatatory action of adenosine on pial arteries of cats and its inhibition by theophylline},
  author={Michael R. Wahl and Wolfgang Kuschinsky},
  journal={Pfl{\"u}gers Archiv},
  year={1976},
  volume={362},
  pages={55-59}
}
SummaryThe effect of adenosine upon pial resistance vessels was studied using local microapplication from the perivascular side and measurement of vascular diameter. Concentration-response curves revealed a concentration-dependent dilatatory effect of adenosine between 10−7 and 10−3 M. The degree of dilatation was independent of initial vessel size (47–260 μ). The dilatations due to adenosine could be reduced by theophylline in a reversible competitive antagonism. Concentration-response curves… CONTINUE READING

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