The digestion rate of protein is an independent regulating factor of postprandial protein retention.
@article{Dangin2001TheDR, title={The digestion rate of protein is an independent regulating factor of postprandial protein retention.}, author={Martial Dangin and Yves Boirie and Clara L. Garcia-Rodenas and Pierre Gachon and Jacques Fauquant and Philippe Callier and Olivier Ball{\`e}vre and Bernard Beaufr{\`e}re}, journal={American journal of physiology. Endocrinology and metabolism}, year={2001}, volume={280 2}, pages={ E340-8 } }
To evaluate the importance of protein digestion rate on protein deposition, we characterized leucine kinetics after ingestion of "protein" meals of identical amino acid composition and nitrogen contents but of different digestion rates. Four groups of five or six young men received an L-[1-13C]leucine infusion and one of the following 30-g protein meals: a single meal of slowly digested casein (CAS), a single meal of free amino acid mimicking casein composition (AA), a single meal of rapidly…
515 Citations
Influence of the protein digestion rate on protein turnover in young and elderly subjects.
- Medicine, ChemistryThe Journal of nutrition
- 2002
In young men, a "fast" protein may be more beneficial than a "slow" one in elderly subjects, to limit body protein loss, and the preliminary results suggest that added nonprotein energy sources to CAS and WP attenuated the differences in both the protein digestion rate and protein gain.
Supplement : Protein Metabolism in Response to Ingestion Pattern and Composition of Proteins Influence of the Protein Digestion Rate on Protein Turnover in Young and Elderly Subjects 1 , 2
- 2002
It has long been recognized that numerous dietary parameters, such as the amount and type of protein and nonprotein energy sources, affect protein metabolism. More recently, we demonstrated that the…
The Rate of Protein Digestion affects Protein Gain Differently during Aging in Humans
- Biology, MedicineThe Journal of physiology
- 2003
During aging, protein gain was greater with WP (rapidly digested protein), and lower with CAS (slowly digesting protein), which suggests that a ‘fast’ protein might be more beneficial than a ’slow’ one to limit protein losses during aging.
Plasma amino acid response after ingestion of different whey protein fractions
- Chemistry, MedicineInternational journal of food sciences and nutrition
- 2009
In conclusion, whole proteins resulted in a more rapid absorption of leucine and branched-chain amino acid into the blood compared with the hydrolysed molecular form of whey protein.
Compared with casein or total milk protein, digestion of milk soluble proteins is too rapid to sustain the anabolic postprandial amino acid requirement.
- Chemistry, MedicineThe American journal of clinical nutrition
- 2006
The results confirm the major role of kinetics in dietary nitrogen postprandial utilization and highlight the paradox of MSPI, which, despite its high Protein Digestibility Corrected Amino Acid Score, ensures a rate of amino acid delivery that is too rapid to sustain the anabolic requirement during the postpr andial period.
Ingestion of Casein in a Milk Matrix Modulates Dietary Protein Digestion and Absorption Kinetics but Does Not Modulate Postprandial Muscle Protein Synthesis in Older Men.
- Chemistry, MedicineThe Journal of nutrition
- 2015
Casein ingestion in a milk matrix delays protein digestion and absorption but does not modulate postprandial muscle protein synthesis when compared to the ingestion of micellar casein only in healthy older men.
Whey protein stimulates postprandial muscle protein accretion more effectively than do casein and casein hydrolysate in older men.
- Medicine, ChemistryThe American journal of clinical nutrition
- 2011
Whey protein stimulates postprandial muscle protein accretion more effectively than do casein and casein hydrolysate in older men, attributed to a combination of whey's faster digestion and absorption kinetics and higher leucine content.
Protein Type, Protein Dose, and Age Modulate Dietary Protein Digestion and Phenylalanine Absorption Kinetics and Plasma Phenylalanine Availability in Humans
- MedicineThe Journal of nutrition
- 2020
Protein type, protein dose, and age modulate dietary protein digestion and amino acid absorption kinetics and subsequent postprandial plasma amino acid availability in vivo in humans.
Effects of Whey, Caseinate, or Milk Protein Ingestion on Muscle Protein Synthesis after Exercise
- MedicineNutrients
- 2016
It is concluded that ingestion of MP, CA or WP causes the initial peak time in muscle protein synthesis to occur at different times (WP, fast; MP, intermediate; CA, slow) and the dairy proteins have a superior effect on muscleprotein synthesis after exercise compared with SP.
Ingestion of a protein hydrolysate is accompanied by an accelerated in vivo digestion and absorption rate when compared with its intact protein.
- Chemistry, BiologyThe American journal of clinical nutrition
- 2009
Ingestion of a protein hydrolysate accelerates protein digestion and absorption from the gut, augments postprandial amino acid availability, and tends to increase the incorporation rate of dietary amino acids into skeletal muscle protein.
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