The differentiation of propafenone from other class Ic agents, focusing on the effect on ventricular response rate attributable to its beta-blocking action

@article{Faber1996TheDO,
  title={The differentiation of propafenone from other class Ic agents, focusing on the effect on ventricular response rate attributable to its beta-blocking action},
  author={Thomas S. Faber and Alan John Camm},
  journal={European Journal of Clinical Pharmacology},
  year={1996},
  volume={51},
  pages={199-208}
}
Propafenone, encainide and flecainide have been categorized as class Ic antiarrhythmic drugs, since they produce similar clinical electrophysiological effects. However, propafenone has also modes of action that differ substantially from pure class Ic activity. The most distinctive electrophysiological difference from other class Ic antiarrhythmic drugs stems from its structural similarity with other beta-adrenoceptor antagonists. The potency of the β-adrenoceptor blocking property of… CONTINUE READING

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