The differential expression patterns of messenger RNAs encoding Nogo-A and Nogo-receptor in the rat central nervous system.

@article{Hasegawa2005TheDE,
  title={The differential expression patterns of messenger RNAs encoding Nogo-A and Nogo-receptor in the rat central nervous system.},
  author={Tomohiko Hasegawa and Koji Ohno and Michio Sano and Takao Omura and Kumiko Omura and Akira Nagano and Kohji Sato},
  journal={Brain research. Molecular brain research},
  year={2005},
  volume={133 1},
  pages={119-30}
}
Nogo-A and Nogo-receptor have been considered to play pivotal roles in controlling axonal regeneration and neuronal plasticity. We investigated the total distribution of Nogo-A and Nogo-receptor mRNAs in the adult rat central nervous system using in situ hybridization histochemistry. Nogo-A is abundantly expressed in both neurons and oligodendrocytes throughout the central nervous system. Interestingly, we could not find any neuron which lacks Nogo-A mRNA expression, indicating that Nogo-A mRNA… CONTINUE READING

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