The differential expression of LCK and BAFF-receptor and their role in apoptosis in human lymphomas.

@article{Paterson2006TheDE,
  title={The differential expression of LCK and BAFF-receptor and their role in apoptosis in human lymphomas.},
  author={Jennifer C. Paterson and Sara Tedoldi and Andrew Craxton and Margaret D. Jones and Martin-Leo Hansmann and Graham Collins and Helen M Roberton and Yasodha Natkunam and Stefano A Pileri and El{\'i}as Campo and Edward A. Clark and David Mason and Teresa Marafioti},
  journal={Haematologica},
  year={2006},
  volume={91 6},
  pages={772-80}
}
BACKGROUND AND OBJECTIVES We explored the expression of LCK and BAFF-R (B-cell activating factor receptor) both of which are known to play a role in signaling and apoptosis, in routine tissue biopsies. It was hypothesized that their expression patterns might yield information on apoptosis as it occurs in normal and reactive lymphoid cells, and also be of value for the detection of lymphoma subtypes. DESIGN AND METHODS Both molecules were studied in paraffin-embedded tissue sections and cell… CONTINUE READING

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