The differential effects of depression on evoked and spontaneous pain behaviors in olfactory bulbectomized rats.

@article{Wang2010TheDE,
  title={The differential effects of depression on evoked and spontaneous pain behaviors in olfactory bulbectomized rats.},
  author={Wei Wang and Wei-Jing Qi and Yang Xu and Jin-Yan Wang and Fei Luo},
  journal={Neuroscience letters},
  year={2010},
  volume={472 2},
  pages={143-7}
}
Although it has been accepted that depression and pain are common comorbidities, their interaction is not fully understood. The current study was aimed to investigate the effects of depression on both evoked pain behavior (thermal-induced nociception) and spontaneous pain behavior (formalin pain) using an olfactory bulbectomy (OB) rat model of depression. Emotional behaviors were assessed by open field and Morris water maze tests. The results showed that the depressed rats exhibited stronger… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

Depression and anxiety behaviour in a rat model of chronic migraine

The Journal of Headache and Pain • 2017
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 25 references

Depression and pain comorbidity: a literature review.

Archives of internal medicine • 2003
View 4 Excerpts
Highly Influenced

Depression shows divergent effects on evoked and spontaneous pain behaviors in rats.

The journal of pain : official journal of the American Pain Society • 2010

Involvement of cholecystokininergic systems in anxiety-induced hyperalgesia in male rats: behavioral and biochemical studies.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2005
View 1 Excerpt

Pain perception in major depression depends on pain

K. J. Bar, S. Brehm, +3 authors H. Sauer
modality, Pain • 2005

Similar Papers

Loading similar papers…