The differential effects of FTY720 on functional recovery and infarct size following myocardial ischaemia/ reperfusion

Abstract

AIM The aim of this study was to evaluate the effects of the sphingosine analogue, FTY720 (Fingolimod), on the outcomes of myocardial ischaemia/reperfusion (I/R) injury. METHODS Two concentrations of FTY720 (1 or 2.5 µM were administered either prior to (PreFTY), or following (PostFTY) 20 minutes' global (GI) or 35 minutes' regional ischaemia (RI) in the… (More)
DOI: 10.5830/CVJA-2016-039

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