The differential diagnosis of dementia using P300 latency.

  title={The differential diagnosis of dementia using P300 latency.},
  author={Evian Gordon and C Kraiuhin and Anthony Harris and Russell Ainslie Meares and Anne L Howson},
  journal={Biological psychiatry},
  volume={21 12},
The P300 component was elicited by an auditory oddball paradigm in 55 normal adults from a wide age range: 19 patients with dementia, 17 patients with depression, and 15 patients with schizophrenia. Normal P300 latency at a given age was predicted by using an age regression equation that had been calculated on the basis of the entire normal sample. Using this procedure, an abnormal delay in latency (greater than 2 SD) was found in approximately 80% of the dementia patients. However, when normal… CONTINUE READING