The differential diagnosis and treatment of normal-pressure hydrocephalus.

  title={The differential diagnosis and treatment of normal-pressure hydrocephalus.},
  author={Michael Kiefer and Andreas Unterberg},
  journal={Deutsches Arzteblatt international},
  volume={109 1-2},
  pages={15-25; quiz 26}
BACKGROUND Normal-pressure hydrocephalus (NPH) arises in adulthood and is characterized by a typical combination of clinical and radiological findings. The mean basal intracranial pressure is normal or mildly elevated. The typical signs of the disease are gait impairment, urinary incontinence, and dementia. The difficulty of distinguishing NPH from other neurodegenerative disorders is the likely reason why some 80% of cases remain unrecognized and untreated. According to current evidence, the… CONTINUE READING