The different facets of protein kinases C: old and new players in neuronal signal transduction pathways.

@article{Amadio2006TheDF,
  title={The different facets of protein kinases C: old and new players in neuronal signal transduction pathways.},
  author={Marialaura Amadio and Fiorenzo Battaini and Alessia Pascale},
  journal={Pharmacological research},
  year={2006},
  volume={54 5},
  pages={317-25}
}
Signal transduction pathways are crucial for cell-to-cell communication. Various molecular cascades allow the translation of distinct stimuli, targeting the cell, into a language that the cell itself is able to understand, thus elaborating specific responses. Within this context, a strategic role is played by protein kinases which catalyze the phosphorylation of specific substrates. The serine/threonine protein kinase C (PKC) enzymes family (at least 10 isoforms) is implicated in the… CONTINUE READING