The different effects of LPS and poly I:C prenatal immune challenges on the behavior, development and inflammatory responses in pregnant mice and their offspring.

@article{Arsenault2014TheDE,
  title={The different effects of LPS and poly I:C prenatal immune challenges on the behavior, development and inflammatory responses in pregnant mice and their offspring.},
  author={Dany Arsenault and Isabelle St-Amour and Giulia Cisbani and Louis-Simon Rousseau and Francesca Cicchetti},
  journal={Brain, behavior, and immunity},
  year={2014},
  volume={38},
  pages={77-90}
}
In recent years, in vivo animal models of prenatal infection have been developed in an attempt to recreate behavioral and neuropathological features associated to a number of neurological and neuropsychiatric disorders. However, these models are still in their emerging phase and a better understanding of how these types of infections relate to adult-onset of brain-related disorders is needed. Here, we undertook an extensive behavioral characterization of both pregnant females and their pups… CONTINUE READING
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