The different distribution of enzymatic collagen cross-links found in adult and children bone result in different mechanical behavior of collagen.

@article{Depalle2018TheDD,
  title={The different distribution of enzymatic collagen cross-links found in adult and children bone result in different mechanical behavior of collagen.},
  author={Baptiste Depalle and Andre G Duarte and Imke A. K. Fiedler and Laurent Pujo-Menjouet and Markus J Buehler and J P Berteau},
  journal={Bone},
  year={2018},
  volume={110},
  pages={
          107-114
        }
}
Enzymatic collagen cross-linking has been shown to play an important role in the macroscopic elastic and plastic deformation of bone across ages. However, its direct contribution to collagen fibril deformation is unknown. The aim of this study is to determine how covalent intermolecular connections from enzymatic collagen cross-links contribute to collagen fibril elastic and plastic deformation of adults and children's bone matrix. We used ex vivo data previously obtained from biochemical… CONTINUE READING