The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide.

Abstract

OBJECTIVE Since modern treatment of rheumatoid arthritis (RA) is shifting toward aggressive antirheumatic therapy in an early phase of the disease, diagnostic tests with high specificity are desirable. A new serologic test (anti-cyclic citrullinated peptide [anti-CCP] enzyme-linked immunosorbent assay [ELISA]) was developed to determine the presence of… (More)

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