The diacylglycerol-binding protein alpha1-chimaerin regulates dendritic morphology.

  title={The diacylglycerol-binding protein alpha1-chimaerin regulates dendritic morphology.},
  author={Philip Buttery and Asim A. Beg and Ben Chih and Arkady Broder and Carol Ann Mason and Peter Scheiffele},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={103 6},
The morphological and functional differentiation of neuronal dendrites is controlled through transcriptional programs and cell-cell signaling. Synaptic activity is thought to play an important role in the maturation of dendritic arbors, but the signaling pathways that couple neuronal activity and morphological changes in dendrites are not well understood. We explored the function of alpha1-chimaerin, a neuronal diacylglycerol-binding protein with a Rho GTPase-activating protein domain that… CONTINUE READING
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