The dextran sulphate sodium (DSS) model of colitis: an overview

@article{Solomon2010TheDS,
  title={The dextran sulphate sodium (DSS) model of colitis: an overview},
  author={Livingstone K Solomon and Sorsiah Mansor and Peter Mallon and Eilish T Donnelly and Margaret Hoper and Morris Loughrey and Stephen Kirk and Keith Gardiner},
  journal={Comparative Clinical Pathology},
  year={2010},
  volume={19},
  pages={235-239}
}
The dextran sulphate sodium model of colitis has demonstrated several correlations with human inflammatory bowel disease and is deemed suitable for investigating pathogenesis, therapeutic options and the dysplasia–adenocarcinoma sequence of inflammatory bowel disease. It is widely applicable to mice, rats, hamsters and guinea pigs. This review explores the features of this model and identifies areas for further research studies.