The developmentally regulated expression of serum response factor plays a key role in the control of smooth muscle-specific genes.

@article{Browning1998TheDR,
  title={The developmentally regulated expression of serum response factor plays a key role in the control of smooth muscle-specific genes.},
  author={Cindy L Browning and Donald E Culberson and Ileana V. Aragon and Rebecca A Fillmore and Jeffrey D Croissant and Robert J. Schwartz and Warren E. Zimmer},
  journal={Developmental biology},
  year={1998},
  volume={194 1},
  pages={18-37}
}
Serum response factor (SRF) is a MADS box transcription factor that has been shown to be important in the regulation of a variety of muscle-specific genes. We have previously shown SRF to be a major component of multiple cis/trans interactions found along the smooth muscle gamma-actin (SMGA) promoter. In the studies reported here, we have further characterized the role of SRF in the regulation of the SMGA gene in the developing gizzard. EMSA analyses, using nuclear extracts derived from… CONTINUE READING

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