The developmental selector AS1 is an evolutionarily conserved regulator of the plant immune response.

@article{Nurmberg2007TheDS,
  title={The developmental selector AS1 is an evolutionarily conserved regulator of the plant immune response.},
  author={Pedro L Nurmberg and Kirsten Knox and B J Yun and Peter C. Morris and Reza Shafiei and Andrew Hudson and Gary John Loake},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2007},
  volume={104 47},
  pages={
          18795-800
        }
}
The MYB-related gene ASYMMETRIC LEAVES 1 (AS1) and its orthologs have an evolutionarily conserved role in specification of leaf cell identity. AS1 is expressed in leaf founder cells, where it functions as a heterodimer with the structurally unrelated AS2 proteins to repress activity of KNOTTED 1-like homeobox (KNOX) genes. AS1 therefore confines KNOX activity to the shoot apical meristem, where it promotes stem cell function through the regulation of phytohormone activities. Here, we show that… CONTINUE READING
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Plant Cell 16:1251–1262

NA McHale, RE Koning
Nurmberg et al. PNAS November • 2004
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