The developmental roles of the extracellular matrix: beyond structure to regulation

@article{Tsang2009TheDR,
  title={The developmental roles of the extracellular matrix: beyond structure to regulation},
  author={Kwok Yeung Tsang and Martin C. H. Cheung and Danny S K Chan and Kathryn Song Eng Cheah},
  journal={Cell and Tissue Research},
  year={2009},
  volume={339},
  pages={93-110}
}
Cells in multicellular organisms are surrounded by a complex three-dimensional macromolecular extracellular matrix (ECM). This matrix, traditionally thought to serve a structural function providing support and strength to cells within tissues, is increasingly being recognized as having pleiotropic effects in development and growth. Elucidation of the role that the ECM plays in developmental processes has been significantly advanced by studying the phenotypic and developmental consequences of… CONTINUE READING

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