The developmental regulation of a novel muscle LIM-protein.

  title={The developmental regulation of a novel muscle LIM-protein.},
  author={M. J. Morgan and Anthony Madgwick and B Charleston and Jennifer M. Pell and Paul Thomas Loughna},
  journal={Biochemical and biophysical research communications},
  volume={212 3},
Using a cDNA clone derived from a human muscle library we have identified a novel and highly conserved 2.3kb homologue which is highly expressed in skeletal muscle. The partial sequence contains at least three LIM domains and shows greatest homology with the group of LIM-proteins associated with the cytoskeleton and focal adhesion plaques which include zyxin and paxillin. This homologue is maximally expressed in differentiated ovine primary muscle cultures. It is also expressed in the ovine… CONTINUE READING