The developmental cell biology of Trypanosoma brucei.

  title={The developmental cell biology of Trypanosoma brucei.},
  author={Keith R Matthews},
  journal={Journal of cell science},
  volume={118 Pt 2},
Trypanosoma brucei provides an excellent system for studies of many aspects of cell biology, including cell structure and morphology, organelle positioning, cell division and protein trafficking. However, the trypanosome has a complex life cycle in which it must adapt either to the mammalian bloodstream or to different compartments within the tsetse fly. These differentiation events require stage-specific changes to basic cell biological processes and reflect responses to environmental stimuli… CONTINUE READING
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