The development of small molecule angiotensin IV analogs to treat Alzheimer's and Parkinson's diseases

@article{Wright2015TheDO,
  title={The development of small molecule angiotensin IV analogs to treat Alzheimer's and Parkinson's diseases},
  author={John W. Wright and Leen H. Kawas and J. Harding},
  journal={Progress in Neurobiology},
  year={2015},
  volume={125},
  pages={26-46}
}
Alzheimer's (AD) and Parkinson's (PD) diseases are neurodegenerative diseases presently without effective drug treatments. AD is characterized by general cognitive impairment, difficulties with memory consolidation and retrieval, and with advanced stages episodes of agitation and anger. AD is increasing in frequency as life expectancy increases. Present FDA approved medications do little to slow disease progression and none address the underlying progressive loss of synaptic connections and… Expand
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