The development of gluconeogenesis in rat liver. Controlling factors in the newborn.

@article{Ballard1971TheDO,
  title={The development of gluconeogenesis in rat liver. Controlling factors in the newborn.},
  author={F. John Ballard},
  journal={The Biochemical journal},
  year={1971},
  volume={124 2},
  pages={265-74}
}
1. Measurements in livers of rats delivered by Caesarian section show a rapid change in the relative proportion of adenine nucleotides. By 20min the ATP/ADP ratio had increased from 1.76 to 8.7 and the value of the relationship [ATP][AMP]/[ADP](2) increased from 1.0 to 4.4. These changes are dependent on the availability of oxygen to the animal. 2. The free [NAD(+)]/[NADH] ratio in the liver cytosol increases from 180 after delivery to reach a maximum of 1010 at 2h, before falling to 540 in the… CONTINUE READING

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