The development of artemisinin resistance in malaria: reasons and solutions

@article{Chrubasik2010TheDO,
  title={The development of artemisinin resistance in malaria: reasons and solutions},
  author={Cosima Chrubasik and Raymond L. Jacobson},
  journal={Phytotherapy Research},
  year={2010},
  volume={24}
}
Despite world‐wide efforts in fighting malaria, this mosquito‐borne infectious disease is a huge burden for the population, especially in tropical and subtropical areas. The WHO recommends artemisinin‐based combination therapy for the treatment of uncomplicated Plasmodium falciparum malaria. However, artemisinin resistance cannot now be ignored. Factors affecting the development of artemisinin resistance include uncontrolled use of artemisinin‐based combination therapy (ACT), mobile populations… 
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ASSESSMENT OF SERUM UREA, CREATININE AND BILIRUBIN LEVELS AFTER INDUCING WISTAR RATS WITH MALARIA AND TREATED WITH ETHANOLIC EXTRACT OF ARTEMISIA ANNUA L. AND ARTEMISININ COMBINATION THERAPY (ACT)

  • Medicine, Biology
  • 2019
The assessment of serum urea, creatinine and bilirubin levels in malaria infested wistar rats treated with the crude extract of Artemisia annua and artemisinin combination therapy (ACT) was investigated and showed that there was a significant decrease in the serum Urea levels of all the experimental groups when compared with the control.

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