The development of animal models for the study of necrotizing enterocolitis.

  title={The development of animal models for the study of necrotizing enterocolitis.},
  author={Chhinder P. Sodhi and Ward Richardson and Steven C. Gribar and David J. Hackam},
  journal={Disease models & mechanisms},
  volume={1 2-3},
Necrotizing enterocolitis (NEC) is the leading cause of death and long-term disability from gastrointestinal disease in preterm infants, and is characterized by acute and chronic intestinal inflammation that may lead to systemic sepsis and multi-system organ failure. NEC typically develops in the preterm infant after the administration of tube feeds, although it may occasionally be seen in full-term babies. Despite extensive clinical experience in the management of patients with NEC, the… CONTINUE READING
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