The development of a zonula occludens in peripheral myelin of the chick embryo. A freeze-fracture study.

@article{Tetzlaff1978TheDO,
  title={The development of a zonula occludens in peripheral myelin of the chick embryo. A freeze-fracture study.},
  author={Wolfram Tetzlaff},
  journal={Cell and tissue research},
  year={1978},
  volume={189 2},
  pages={187-201}
}
Sciatic nerves of chick embryos, 12 to 18 days incubation, were examined in freeze-fracture replicas with special emphasis placed on the development of tight junctional contacts in the myelin sheaths. In stages of beginning myelination short isolated particulate chains (focal tight junctions) appear in fracture faces of the adjacent membranes in the outer myelin lamellae, i.e., the outer mesaxon. In stages of progressing myelination these tight junctional elements elongate and become more… CONTINUE READING