The development of a model for the homing of multiple myeloma cells to human bone marrow.

@article{Urashima1997TheDO,
  title={The development of a model for the homing of multiple myeloma cells to human bone marrow.},
  author={Mitsuyoshi Urashima and Ben P. Chen and Sai-juan Chen and Geraldine S. Pinkus and Roderick Terry Bronson and D A Dedera and Yoshiyuki Hoshi and Gerrard K. H. Teoh and Atsushi Ogata and S P Treon and Dharminder Chauhan and K. C. Anderson},
  journal={Blood},
  year={1997},
  volume={90 2},
  pages={754-65}
}
Prior in vitro studies have suggested a role of adhesion molecules, bone marrow stromal cells (BMSCs), and cytokines in the regulation of human multiple myeloma (MM) cell growth and survival. Although in vivo models have been developed in severe combined immunodeficient (SCID) mice that support the growth of human MM within the murine BM microenvironment… CONTINUE READING