The development and genetic diversity of H5N1 influenza virus in China, 1996-2006.

@article{Duan2008TheDA,
  title={The development and genetic diversity of H5N1 influenza virus in China, 1996-2006.},
  author={Lian Duan and Justin Bahl and Gavin J D Smith and Jia Wang and Dhanasekaran Vijaykrishna and Li Juan Zhang and Jin Xia Zhang and Keng Sheng Li and Xiao Hui Fan and Chung Lam Cheung and Kai Huang and Leo Lit Man Poon and Kennedy Francis Shortridge and Robert James Webster and Joseph Sriyal Malik Peiris and Hualan Chen and Yi Guan},
  journal={Virology},
  year={2008},
  volume={380 2},
  pages={243-54}
}
Since it was first detected in 1996, the Goose/Guangdong/1/1996 (Gs/GD) H5N1 influenza virus and its reassortants have spread to over 60 countries, with over 20 distinct genetic reassortants previously recognized. However, systematic analysis of their interrelationship and the development of genetic diversity have not been explored. As each of those reassortants was first detected in China, here 318 full-length H5N1 virus genomes isolated from 1996 to 2006 in this region were phylogenetically… CONTINUE READING