The developing use of heterozygous mutant mouse models in brain monoamine transporter research.

@article{Kalueff2007TheDU,
  title={The developing use of heterozygous mutant mouse models in brain monoamine transporter research.},
  author={Allan Kalueff and Renee F. Ren-Patterson and Dennis L. Murphy},
  journal={Trends in pharmacological sciences},
  year={2007},
  volume={28 3},
  pages={122-7}
}
5-Hydroxytryptamine (5-HT), dopamine and norepinephrine are important monoamine neurotransmitters implicated in multiple brain mechanisms and regulated by high-affinity transmembrane monoamine transporters. Although knockout mice lacking 5-HT, dopamine or norepinephrine transporters are widely used to assess brain monoamine processes, these models have… CONTINUE READING