The developing story of Sprouty and cancer

  title={The developing story of Sprouty and cancer},
  author={Samar Masoumi-Moghaddam and Afshin Amini and David L Morris},
  booktitle={Cancer and Metastasis Reviews},
Sprouty proteins are evolutionarily conserved modulators of MAPK/ERK pathway. Through interacting with an increasing number of effectors, mediators, and regulators with ultimate influence on multiple targets within or beyond ERK, Sprouty orchestrates a complex, multilayered regulatory system and mediates a crosstalk among different signaling pathways for a coordinated cellular response. As such, Sprouty has been implicated in various developmental and physiological processes. Evidence shows… CONTINUE READING

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