The developing story of Sprouty and cancer

@inproceedings{MasoumiMoghaddam2014TheDS,
  title={The developing story of Sprouty and cancer},
  author={Samar Masoumi-Moghaddam and Afshin Amini and David L Morris},
  booktitle={Cancer and Metastasis Reviews},
  year={2014}
}
Sprouty proteins are evolutionarily conserved modulators of MAPK/ERK pathway. Through interacting with an increasing number of effectors, mediators, and regulators with ultimate influence on multiple targets within or beyond ERK, Sprouty orchestrates a complex, multilayered regulatory system and mediates a crosstalk among different signaling pathways for a coordinated cellular response. As such, Sprouty has been implicated in various developmental and physiological processes. Evidence shows… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 30 extracted citations

Sprouty2—a Novel Therapeutic Target in the Nervous System?

Molecular Neurobiology • 2018
View 7 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 177 references

Similar Papers

Loading similar papers…