The determination of hydroxyproline.

  title={The determination of hydroxyproline.},
  author={R E NEUMAN and M A Logan},
  journal={The Journal of biological chemistry},
  volume={184 1},
There has been a great need for a satisfactory method for the determination of hydroxyproline to facilitate the study of the composition of proteins. Lang (1) and Waldschmidt-Leitz and Akabori (2) developed a calorimetric estimation involving oxidation to pyrrole with sodium hypochlorite and color formation with isatin or p-dimethylaminobenzaldehyde. However, oxidation was said to be incomplete and a correction factor was necessary. Dakin (3) and Bergmann (4) estimated hydroxyproline by… CONTINUE READING
Highly Influential
This paper has highly influenced 17 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS


Publications citing this paper.
Showing 1-10 of 207 extracted citations


Publications referenced by this paper.

hp://w w w D ow nladed from Robert E

  • R. Adams, G. H. Coleman, Org
  • Syntheses,
  • 1922

Similar Papers

Loading similar papers…