The determination of collagen and elastin in tissues.

@article{Neuman1950TheDO,
  title={The determination of collagen and elastin in tissues.},
  author={Robert E. Neuman and Milan A. Logan},
  journal={The Journal of biological chemistry},
  year={1950},
  volume={186 2},
  pages={
          549-56
        }
}
In the study of the occurrence and distribution of collagen in normal and pathological tissue and its formation and development in the embryo there has been need for aq accurate method to determine this substance in small amounts of tissue. Spencer, Morgulis, and Wilder (1) devised a method based on conversion of collagen to gelatin followed by the determination of the nitrogen of the gelatin precipitated with tannic acid. There is no assurance that only gelatin is extracted and precipitated… Expand
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