The detection of hydroxyl radicals in vivo.

  title={The detection of hydroxyl radicals in vivo.},
  author={Wolfhardt Freinbichler and Loria Bianchi and Maria Alessandra Colivicchi and Chiara Ballini and Keith F. Tipton and Wolfgang Linert and Laura Della Corte},
  journal={Journal of inorganic biochemistry},
  volume={102 5-6},
Several indirect methods have been developed for the detection and quantification of highly reactive oxygen species (hROS), which may exist either as free hydroxyl radicals, bound "crypto" radicals or Fe(IV)-oxo species, in vivo. This review discusses the strengths and weaknesses associated with those most commonly used, which determine the hydroxylation of… CONTINUE READING