The detection of circulating immune complexes in renal transplant patients.

@article{Smith1980TheDO,
  title={The detection of circulating immune complexes in renal transplant patients.},
  author={Malcolm D. Smith and Pierre J. Verroust and Philip J. Griffin and John R. Salaman},
  journal={Clinical and experimental immunology},
  year={1980},
  volume={39 1},
  pages={141-5}
}
The Raji cell assay and radiolabelled Clq binding method were used to detect circulating immune complexes in the sera of renal transplant patients. Complexes were found in seven of twelve patients using the Raji cell assay; only one serum sample was positive by the Clq method. In five patients the complexes were detected prior to the clinical diagnosis of rejection and in those in whom treatment reversed the rejection the complexes rapidly disappeared. The presence of complexes correlated with… CONTINUE READING

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