The detection of bovine lactoferrin binding protein on Trypanosoma brucei.

@article{Tanaka2004TheDO,
  title={The detection of bovine lactoferrin binding protein on Trypanosoma brucei.},
  author={Tetsuya S. Tanaka and Yukie Abe and Noboru Inoue and Woan-Sub Kim and Haruto Kumura and Hideyuki Nagasawa and Ikuo Igarashi and Kei-ichi Shimazaki},
  journal={The Journal of veterinary medical science},
  year={2004},
  volume={66 6},
  pages={619-25}
}
Trypanosoma brucei, the causative agent of sleeping sickness in humans, requires transferrin (TF) for growth. Therefore, T. brucei has a TF receptor that allows it to obtain iron from TF. Lactoferrin (LF), a member of the TF family protein, is an iron-binding protein that is found in most biological fluids of mammals. LF has been shown to interact with some bacteria species by specific receptor-ligand binding. We examined the ability of T. brucei to bind bovine LF (bLF) by using a fluorescence… CONTINUE READING
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