The detection of CMV pp65 and IE1 in glioblastoma multiforme

  title={The detection of CMV pp65 and IE1 in glioblastoma multiforme},
  author={Kenneth G. Lucas and Lei Bao and Richard Bruggeman and Kimberly Dunham and Charles S. Specht},
  journal={Journal of Neuro-Oncology},
Glioblastoma multiforme (GBM) is a highly lethal brain tumor affecting children and adults, with the majority of affected individuals dying from their disease by 2 years following diagnosis. Other groups have reported the association of cytomegalovirus (CMV) with GBM, and we sought to confirm these findings in a large series of patients with primary GBM from our institution. Immunohistochemical analysis of paraffin embedded tissue sections was performed on 49 newly diagnosed GBM tumors, the… CONTINUE READING
46 Citations
48 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 46 extracted citations


Publications referenced by this paper.
Showing 1-10 of 48 references

Detection of human cytomegalovirus in different histological types of gliomas

  • ME Scheurer
  • Acta Neuropathol
  • 2008
Highly Influential
4 Excerpts

Efficacy of a phase II vaccine targeting cytomegalovirus antigens in newly-diagnosed GBM

  • D Mitchell
  • J Clin Oncol
  • 2008
1 Excerpt

Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics

  • JG Zhang
  • Clin Cancer Res
  • 2007
1 Excerpt

Similar Papers

Loading similar papers…