The design of the optic nerve in fish.

  title={The design of the optic nerve in fish.},
  author={J. Scholes},
  journal={Visual neuroscience},
  volume={7 1-2},
Fish have large eyes, with short optic nerves that are continually flexed by compensatory eye movements during swimming. Here, I review the tissue construction of the fish optic nerve, to see how the glia and axons are adapted to withstand these mechanical stresses, which are not normally encountered by CNS tissue within the skull. As in other lower vertebrates, the optic nerve astrocytes are highly unusual: their intermediate filaments are composed of cytokeratins (Giordano et al., 1989), not… CONTINUE READING