The design and synthesis of substituted biphenyl libraries.

  title={The design and synthesis of substituted biphenyl libraries.},
  author={Michael R. Pavia and Michael P. Cohen and Garrett J. Dilley and Gloria R. Dubuc and Tracy L. Durgin and F W Forman and Mark E Hediger and Gilles Milot and Timothy S. Powers and Irving Sucholeiki and Shi-ning Zhou and David G Hangauer},
  journal={Bioorganic & medicinal chemistry},
  volume={4 5},
A novel scaffold system for the generation of diversity libraries has been designed which allows for rapid modification not only of functional groups, but their spatial arrangements as well. The biphenyl scaffold allows for display of three or four diverse functional groups in a wide variety of spatial arrangements depending on the substitution pattern… CONTINUE READING