The desaturation and elongation of linolenic acid and eicosapentaenoic acid by hepatocytes and liver microsomes from rainbow trout (Oncorhynchus mykiss) fed diets containing fish oil or olive oil.

@article{Buzzi1996TheDA,
  title={The desaturation and elongation of linolenic acid and eicosapentaenoic acid by hepatocytes and liver microsomes from rainbow trout (Oncorhynchus mykiss) fed diets containing fish oil or olive oil.},
  author={Marina. Buzzi and R. James Henderson and John R. Sargent},
  journal={Biochimica et biophysica acta},
  year={1996},
  volume={1299 2},
  pages={235-44}
}
The products of desaturation and elongation of [1-14C]18:3(n - 3) and [1-14C]20:5(n - 3) were studied using hepatocytes and microsomes prepared from livers of trout maintained on diets containing either olive oil or fish oil, to establish the extent to which the formation of 22:6(n - 3) was enhanced in the absence of dietary 22:6(n - 3) and to investigate the pathway(s) of conversion of 18:3(n - 3) and 20:5(n - 3) to 22:6(n - 3). Levels of 20:5(n - 3) and 22:6(n - 3) in the total lipid of… CONTINUE READING
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