The derivation of clinical-grade human embryonic stem cell lines.

@article{Skottman2006TheDO,
  title={The derivation of clinical-grade human embryonic stem cell lines.},
  author={Heli Skottman and M. Sirac Dilber and Outi Hovatta},
  journal={FEBS letters},
  year={2006},
  volume={580 12},
  pages={2875-8}
}
The pluripotent nature of human embryonic stem cells (hESC) has attracted great interest in using them as a source of cells or tissue in cell therapy. However, in order to be used in regenerative medicine, the pluripotent hESC lines should be established and propagated according to good manufacturing practice quality requirements. The cultures should be animal substance free in order to exclude the risk of infections and immunogenity. They should also be genetically and epigenetically normal… CONTINUE READING