The derivation and use of mice which do not harbour lactobacilli in the gastrointestinal tract.

@article{Tannock1984TheDA,
  title={The derivation and use of mice which do not harbour lactobacilli in the gastrointestinal tract.},
  author={Gerald W. Tannock and R D Archibald},
  journal={Canadian journal of microbiology},
  year={1984},
  volume={30 6},
  pages={849-53}
}
Penicillin treatment used in conjunction with germfree technology has allowed the derivation of a colony of BALB/c mice which do not harbour lactobacilli in the gastrointestinal tract. The animals continue to harbour Gram-negative anaerobes and coliforms, but not enterococci or filamentous segmented ileal microbes. Isolates of lactobacilli from rodents were able to colonize the gastrointestinal tract of the mice; and isolate from a fowl could not establish in these animals.